Culturally Responsive Education (CRE) refers to a comprehensive ecosystem of "pedagogy, curriculum, theories, attitudes, practices and instructional materials that center students' culture, identities and contexts throughout education systems" (Peoples, 2019). In the context of these simultaneous and complementary efforts, culturally responsive measures help ensure that what students are taught and assessed on align to learning outcomes in step with their local contexts and daily experiences, and which treat these experiences as valid and powerful sources of knowledge. This brief from the Region 19 Comprehensive Center provides an overview of CRE and provides examples of culturally responsive measures.