A course is described where students are engaged in an inquiry-based quarter-long research project to synthesize a known pharmaceutical target. Students use literature search engines, such as Reaxys and SciFinder, and the primary chemical literature as resources to plan and perform the synthesis of their pharmaceutical target. Through this…

A multiweek protein purification suite, suitable for upper-division biochemistry or biotechnology undergraduate students, is described. Students work in small teams to isolate the enzyme lactate dehydrogenase (LDH) from a nontraditional tissue source, mammalian blood, using a sequence of three column chromatographic procedures: ion-exchange, size…

We present an innovative course-based undergraduate research experience curriculum focused on the characterization of single point mutations in p53, a tumor suppressor gene that is mutated in more than 50% of human cancers. This course is required of all introductory biology students, so all biology majors engage in a research project as part of…

Object images are identified more efficiently after prior exposure. Here, the authors investigated shape representations supporting object priming. The dependent measure in all experiments was the minimum exposure duration required to correctly identify an object image in a rapid serial visual presentation stream. Priming was defined as the change…

This study examines first graders' epistemic reasoning, in tacit "practical epistemologies" reflected in thinking about an investigation of their own design. I analyzed children's epistemic reasoning, following a design experiment scaffolding increasing regulation of scientific inquiry in a domain they studied in depth. Participants…

Graphic design's messages can reach across streets and across the globe; they can bring together countries, communities and strangers for a common cause; they can also serve to divide otherwise amenable neighbors. Design students must fully understand this potential reach and thus the responsibility they have to create tolerant, informed messages.…

In a study to evaluate an approach for improving the critical thinking skills of middle school science students, 60 students were given the assignment of completing three guided laboratory activities and writing a report for each. In writing their reports, students were expected to identify the manipulated variable, identify the responding…

This course of study is aligned with the California State Science Framework and provides students with the physics content needed to become scientifically and technologically literate and prepared for post-secondary science education. Framework themes incorporated into the course of study include patterns of change, evolution, energy, stability,…