The OECD Programme for International Student Assessment (PISA) examines what students know in reading, mathematics and science, and what they can do with what they know. It provides the most comprehensive and rigorous international assessment of student learning outcomes to date. Results from PISA indicate the quality and equity of learning outcomes attained around the world, and allow educators and policy makers to learn from the policies and practices applied in other countries. This is one of six volumes that present the results of the PISA 2018 survey, the seventh round of the triennial assessment. "Volume VI: Are Students Ready to Thrive in an Interconnected World?" explores students' ability to examine issues of local, global and cultural significance; understand and appreciate the perspectives and worldviews of others; engage in open, appropriate and effective interactions across cultures; and take action for collective well-being and sustainable development. The volume explores students' outcomes on the cognitive test and corresponding questionnaire in addition to their experiences of global and intercultural learning at school and beyond. [The development of this volume was guided by Andreas Schleicher and Yuri Belfali and managed by Miyako Ikeda. This volume was drafted by Tarek Mostafa and edited by Marilyn Achiron and Susan Copeland. For "PISA 2018 Results: Effective Policies, Successful Schools. Volume V," see ED608394.]