A multi-centre clinical trial involves the implementation of the same clinical protocol at several independent investigational centres. Multi-centre clinical trials may be preferable to single-centre trials, but their implementation and management is more complex. EU-funded collaborative projects involve several participating organizations and…

The method for producing monoclonal antibodies (MAbs) was first published in 1975. MAbs have revolutionised research, diagnosis, and disease treatment approaches. While students need a good understanding of MAb production, teaching the key steps via traditional methods can be challenging. Numerous resources exist, but these focus on hybridoma…

Purpose: This study examined 46 articles in total, which yielded 5 recurring themes: perceived discrimination, language barriers, socioeconomic barriers, cultural barriers and educational/knowledge barriers. The two most dominant themes found were the inability to speak the country's primary language and belonging to a culture with different…

In step with the worldwide trend for higher educational institutes to establish areas of research emphasis,the accumulation of resources in key areas has become common practice in veterinary faculties. Although there are perceived logical benefits to research prioritisation, there have been very little critical retrospective analyses of research…

This study explores the views and experiences of knowledge translation of 14 Australian public health academics. Capacity to engage in knowledge translation is influenced by factors within the academic context and the interaction of the academic and policy environments. Early and mid-career researchers reported a different set of experiences and…

"Ethics in practice" are the ethical dilemmas that arise during the conduct of research. In this article, we describe the ethical issues we faced when conducting an exploration of the experiences of 19 potential living kidney donors, and demonstrate how reflexivity can guide the ethical decision-making throughout the research process. We…

Background: The history of ethical guidelines addresses protection of human rights in the face of violations. Examples of such violations in research involving people with intellectual disabilities (ID) abound. We explore this history in an effort to understand the apparently stringent criteria for the inclusion of people with ID in research, and…

Enterprise risk management strategies were used to develop a regulatory and operational framework for a new multi-partner Research Institute that will house up to 900 staff from four different institutions in Queensland, Australia. The Institute will operate in a business environment while functioning as a research resource for the higher…

This article reports on the pilot work for a collaborative National Health and Medical Research Council project in Australia involving education and health professionals to improve the health and well-being of young people who have an intellectual disability. The pilot study was a qualitative exploration of teacher experiences using a health diary…

Axons undergo Wallerian degeneration distal to a point of injury. Experimental investigations have documented many of the cellular and molecular events that underlie this behaviour. Since relatively little is known about such events in human CNS pathologies and current experimental intervention strategies indicate the possibility of significant…

An initial survey of medical information resources in New South Wales, Queensland, and Victoria, Australia, reveals a lack of adequate collections, insufficiently trained staff, few formal lines of communication between service providers, and paucity of mechanisms to ensure user awareness of available services. Detailed proposals are provided for…

Approximately 300 Australian users and non-users of the biomedical computerized data base, MEDLARS, were surveyed by mailed questionnaire in an attempt to determine the needs of present and potential users of the system and their prior experiences with computerized as well as other information services. Results of the survey reveal: (1) an…