Campus-based efforts to reduce alcohol and other drug abuse and violence (AODV) will be more successful if they involve a wide range of stakeholders--including students--who can contribute to the program's design, implementation, and evaluation. Students provide a unique perspective on AODV prevention, and they can also bring a certain authority to the issue: college presidents and other campus administrators pay attention when students speak about AODV issues in a responsible and informed way. Effective prevention requires the development of an evidence-based strategic plan that defines the program's goals and objectives and outlines specific strategies and activities to carry out those aims. Some AODV programs have succeeded in involving students strategically and effectively by reconceptualizing their relationship with other students as an opportunity to mentor the next generation of prevention leaders. The four institutions featured here exemplify this approach to student leadership: the University of Missouri-Columbia, Arizona State University, the University of North Carolina Wilmington (UNCW), and the University of Southern Maine (USM). This orientation affects how AODV prevention staff select and train students, the types of work they do, and how their experience is evaluated. (Contains 2 resources and 4 online resources.)