The "Annual Disability Statistics Compendium" and its complement, the "Annual Disability Statistics Supplement" (ED620436), are summaries of statistics about people with disabilities and about the government programs which serve them. The Compendium, presents key overall statistics on topics including the prevalence of disability, employment among persons with disabilities, rates of participation in disability income and social insurance programs, and other statistics. The "2021 Annual Disability Statistics Compendium" includes a new section on Voting and Registration, which presents summarized statistics on voting and registration of people with and without disabilities in the 2020 presidential elections. Additionally: (1) The tables presenting change in employment and poverty gaps between people with disability and no disability have been removed this year; (2) The source of all statistics previously reported from the American Community Survey 1-year estimates has changed to the American Community Survey public use microdata sample; and (3) Most statistics based on the American Community Survey public use microdata sample are reported for the age group 18-64 years. A companion "Annual Report" (ED620438) is available, providing graphic representations of key findings. [For the 2020 Compendium, see ED613086.]