A process for adapting a case study as a high impact practice for undergraduate microbiology classes is described and its use in assessing global awareness as an institutional outcome at the course level. Documenting the student learning of content objectives and retention is addressed. Four student artifacts are assessed with an adaption of American Association of Colleges & Universities (AAC&U) rubrics at various points in the unit for formative and summative assessment. Student attrition, critical thinking, global awareness, and engagement in biology are addressed.