This paper outlines the findings from an integrated diagnostic assessment of manifestations of giftedness in senior preschoolers and their interest in professions. The authors investigated the relationship between manifestations of a certain type of giftedness in children and their interest in a certain group of professions. The assessment of manifestations of giftedness was conducted based on a methodology developed by A.I. Savenkov. This methodology helps assess the presence of traits of the following 10 major types of giftedness: intellectual, creative, academic, pictorial, musical, literary, performing, technical, leadership, and sporting. The study of interest in professions was conducted based on E.A. Klimov's Differential-Diagnostic Questionnaire, which had been adapted for preschoolers. The study helped draw the following conclusions: (1) based on pedagogue and parent reports, the type of giftedness that is detected most often in senior preschoolers is the pictorial type, followed by sporting giftedness, and then leadership giftedness; (2) parent assessments of manifestations of giftedness in their children tend to be significantly higher than teacher assessments when it comes to pictorial, musical, literary, leadership, and sporting giftedness; (3) the number of preschoolers with multiple manifestations of giftedness (a high level on three or more types) is significantly larger than the number of preschoolers with manifestations of one-to-two types of giftedness; (4) gifted children tend to have a clear-cut interest in a certain group of professions; (5) there is a significant correlation (at the 0.01 level based on the Pearson correlation coefficient) between leadership giftedness (teacher assessments) and interest in professions within the 'Man -- Man' group, between academic giftedness (teacher assessments) and interest in the 'Man -- Technology' group of professions, and between creative giftedness (parent assessments) and interest in the 'Man -- Technology' group of professions. The results could be utilized in implementing efforts to provide pedagogical support for and early vocational guidance to gifted children in kindergartens and institutions of supplementary learning for preschoolers.