This study examined whether varying dimensions of teacher-child relationship quality and gender moderated associations between knowledge of negative emotion-eliciting situations and peer victimization among Black preschoolers (60 boys, 54 girls) who ranged in age from 35 to 65 months. Fifty-one children had a Black teacher, 46 had a White teacher, and 17 had a Latine teacher. All teachers were female. Knowledge of negative emotion-eliciting situations was assessed directly in the fall. Lead teachers reported on teacher-child relationship quality between September and December. A second teacher completed peer victimization ratings in the spring of the following year. When teacher-child closeness was high, there was a positive association between knowledge of negative emotion-eliciting situations and physical victimization, but a negative association emerged when teacher-child closeness was low. In accord with the victim schema model that undergirded this study, knowledge of negative emotion-eliciting situations was negatively related to physical victimization for children who experienced high teacher-child conflict and dependency. Black teachers perceived more relational victimization. Our findings highlight the need for further examination of peer victimization among young Black children and suggest that identifying the individual and ecological correlates of peer victimization should be a priority for school psychologists working in early educational contexts.