Introduction: The main objective of the research was to analyze the existence of prejudice among university students of Melilla Campus (Spain) towards migrants who cross the border illegally. The role of educators and health professionals has a special interest in this context; they are who will have more contact with them. This requires the development of research on this subject. Method: The study focuses on knowing if there are prejudiced attitudes among university students, using the scale of subtle and blatant prejudice towards illegal immigrants in the Autonomous city of Melilla. The sample consists of 205 students. It has been used empirical-analytical methodology to be an ex post facto correlational study in which descriptive and inferential analyzes were performed. Results: The results show no significant differences regarding the prejudicial attitudes and gender variable. By contrast, the data indicates that the variable qualifications and culture of origin affect the attitudes which university students show about migrants. Discussion and Conclusion: The results of the study highlight the existence of college students with certain amount of prejudice against irregular migrants. Concerned that students with social qualifications, such as primary education and nursing show this type of ratings to people who, for various reasons, have had to emigrate from their countries (either by poverty, wars, political persecution or sexual orientation).