Launching a successful new online learning initiative or expanding existing online learning offerings takes careful planning and preparation. Online learning is an institution-wide endeavor, involving multiple departments, functions, and personnel, many of which require modifications or rethinking to meet the needs of fully online learners. Leaders tasked with heading up institutional online initiatives may be unaware of everything that needs to be done to initiate or examine online learning. This article offers a systematic framework to guide strategic planning that is based upon the unique needs and circumstances of online learning and online learners and the institutions who recruit, educate, and graduate them.