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Direct linkYates, Nicholas D. J.; Brabham, Robin L.; Spears, Richard J.; Keenan, Tessa; Helliwell, Philip A.; Pugh, David S.; Parkin, Alison; Hurst, Glenn A.; Fascione, Martin A. – Journal of Chemical Education, 2019
A laboratory experiment introducing the concept of chemical bioconjugation of proteins to undergraduate students in a therapeutically relevant context was developed. Initially, students installed an aldehyde functionality into a protein via the oxidation of the N-terminal threonine residue of the cholera toxin subunit B (CTB) protein, which was…
Descriptors: College Science, Undergraduate Study, Science Laboratories, Chemistry
Garrett, Brendan; Matharu, Avtar S.; Hurst, Glenn A. – Journal of Chemical Education, 2017
A laboratory experiment was developed to investigate the rheological properties of a green calcium-cross-linked alginate gel as an alternative to the traditional borax-cross-linked poly(vinyl alcohol) gel. As borax is suspected of damaging fertility and the unborn child, a safe, green alternative is necessary. The rheological properties of a…
Descriptors: Laboratory Experiments, Science Experiments, Science Laboratories, Scientific Concepts
Mackenzie, Lucy S.; Tyrrell, Helen; Thomas, Robert; Matharu, Avtar S.; Clark, James H.; Hurst, Glenn A. – Journal of Chemical Education, 2019
A laboratory experiment was developed to introduce students to waste valorization. This is the process of reusing, recycling, or composting from wastes, useful products, or sources of energy. In this laboratory experiment, waste valorization is demonstrated through transforming waste orange peel (WOP) into a marmalade-type gel by extracting a…
Descriptors: Wastes, Laboratory Experiments, Science Instruction, Chemistry
Hurst, Glenn A.; Bella, Malika; Salzmann, Christoph G. – Journal of Chemical Education, 2015
A laboratory experiment was developed to follow the gelation of a polyvinyl alcohol (PVA) solution upon addition of borax by using rotational viscometry. The rheological properties of the gel were examined, measuring the dependence of viscosity and shear stress on the shear rate. Time-dependent studies were also conducted in which the viscosity of…
Descriptors: Chemistry, College Science, Science Instruction, Science Experiments
