This predictive, cross-sectional study aimed to determine the metacognitive online reading and navigational strategies and their relation to the reading performance of Grade 11 HUMSS Students of Pedro T. Mendiola Sr. Memorial National High School. Furthermore, the study also investigated which factors of metacognitive online reading and navigational strategies significantly influence the respondents' reading performance. One hundred twenty-five (125) students selected through simple random sampling participated in the study. Data were gathered using a Google Form and reading fluency test. Descriptive Statistics such as weighted mean, Pearson-Product correlation, and regression analysis were used to interpret the data. The students' extent of the metacognitive online reading and navigational strategies is high, while the students' reading performance is instructional. The metacognitive online reading strategy is strongly related to reading performance. The navigational strategy is moderately related to reading performance. All indicators of metacognitive online learning strategy significantly predict reading performance. Only mixed overview as an indicator of navigational strategy significantly predicts the reading performance. Senior High school students who used metacognitive online reading navigational strategies had definite reading goals in mind and knew how to accomplish them. Students need teacher support at the instructional reading performance level. The metacognitive and navigational strategies significantly predict and influence the respondents' reading performance.