With a renewed commitment to systematic efforts as school leaders use multi-tiered systems of supports to meet students' multiple needs as educators navigate through the pandemic era, it is helpful to learn from implementers who screened successfully prior to the pandemic. This model demonstration paper features the experiences of four middle and two high schools in one district that were in the first year of implementing a multi-tiered system of support (MTSS). The authors summarize the procedures, key findings, and lessons learned regarding conducting systematic screening at middle and high school level.