Although students have been taking the Florida Comprehensive Assessment Test (FCAT) Science test for a few years, the State included the performance on the Science test in the school grade calculations for the first time in 2006-07. Although no official guidelines exist presently, the Science scores may also be incorporated in the NCLB Adequately Yearly Progress requirements in the near future. With the growing importance of the Science test, it becomes increasingly desirable to have some way of predicting the performance of students. In other FCAT testing areas, prediction formulas and cutoff scores for success have been developed by this office and made available to schools for several years. However, because the Science test is relatively new and because it is administered in only Grades 5, 8, and 11, prediction for this test must proceed along different lines. This paper presents the results of an analysis directed toward predicting students' Science scores based on their performance on the FCAT Mathematics test of the previous year. [For the 2006-07 edition of this report, see ED538076.]