This study aimed to investigate Philippine indigenous learners' speaking difficulties in English Semantics. The objectives was to identify indicators of poor vocabulary, processing and expressing of information. It was a qualitative research through case studies of five Grade 2 Indigenous Peoples (IP) learners in Echague, Isabela, Philippines. Data collection was done through observation and oral assessments activities. Instruments include checklist of speaking difficulties signified by inadequacy in English vocabulary; and constructed oral assessment activities in English. Data gathered were qualitatively analysed. Findings revealed that all the five indigenous learner-participants demonstrated English vocabulary deficiency to name depicted objects in the surroundings. They had struggles in reciting week-days, months and in citing common Philippine events. They had difficulty in conveying illustrated antonyms and synonyms. These findings denote a language intervention to improve essential skills in English semantics. This study can be an alternative to investigate problems in other language literacy domains.