The goal of this study was to understand which factors, related to school science, can interfere with engagement of students-at-risk-of-dropping-out with school science and to know what kind of activities and teaching strategies are adequate to these students. This case-study involved a chemistry-teacher and ten male students. Data was based on teacher's interview, teacher's and students' notes regarding activities implementation and students' questionnaires. Results show that linking science with society by means of practical activities--that are student centred and require agency, autonomy, and the mobilization of complex competencies--facilitated the students' engagement with school science. (Contains 2 tables.)