Broward County Public Schools' Research Services department uses logistic regression analysis to compute an indicator to predict student enrollment in advanced high school courses, for students entering ninth grade for the first time. This prediction indicator, along with other student characteristics, supports high school guidance staffs in determining whether a student will be likely to enroll--and do well--in a rigorous upper-level course, such as Advanced Placement, Dual Enrollment, or International Baccalaureate courses. This study examined the validity and utility of these prediction indicators. Results revealed that the predictors accurately indicated which students (a) were more likely to actually enroll in an upper-level course, (b) were more likely to receive grades of "C" or higher in the course, (c) were more likely to pass the Advanced Placement examination, and (d) were more likely to enroll in an upper-level course earlier in their high school career. The findings in this study support the validity and usefulness of the prediction indicators. (Contains 5 tables and 2 figures.)