Authentic student-led inquiry and exposure to scientific research impact students' science career choices. Given Australian students decline in STEM [science, technology, engineering and mathematics] skills, knowledge of whether such programmes impact student learning is critical. This research examined the short-term impact of an authentic, hands-on research mentor programme on rural student's science skills. Nine Year 10 students participated in a science academic research programme leading to scientific publications and students collecting of first-hand data from international experiments on a major world-wide health issue. The NSW [New South Wales] Department of Education Year 10 VALID [Validation of Assessment for Learning and Individual Development] assessment scores of this intervention group were compared to a control group. Intervention students had significantly higher overall scores as well as significantly higher scores in 21st century skills. These results were supported by student's self-assessment of their learning growth. Our study suggests authentic science research mentor programmes are pedagogically advantageous for Year 10 high achieving rural students. Educators' willingness to embrace these innovative approaches has the potential to produce the next generation of scientists.