English-Spanish cognates are words that possess identical or nearly identical spellings and meanings in both English and Spanish as a result of being derived mainly from Latin and Greek. Of major importance is the fact that many of the more than 20,000 cognates in English are academic vocabulary words, terms essential for comprehending school texts. The Texas 2x2 Reading List is a list of recommended reading books for children ranging in ages from pre-school to the early primary grades. The list is published yearly by the Children's Round Table, a division of the Texas Library Association. The books that comprise the Texas 2x2 Reading List are a rich source of vocabulary and contain many English-Spanish cognates. Teachers can use the Texas 2x2 picture books to create a cognate vocabulary lesson that can be taught as a companion to a picture book read-aloud. The purpose of this paper is to present some of the different types of cognate vocabulary lessons that may be created to accompany a picture book read-aloud. The lessons are based on the morphological and spelling regularities between English and Spanish cognates and can be used to teach students how to convert words from one language to another. Examples of the different types of regularities and the Texas 2x2 books that contain them are included, as is an example cognate vocabulary lesson plan to accompany the picture book, Oddrey (Whamond, 2012).