The present study examined proximal variables in families of children prenatally exposed to cocaine and enrolled in a large-scale intervention program. Fifty-six high-risk families of children enrolled in the center-based (n = 30) or home-based (n = 26) intervention of the Linda Ray Intervention Program were interviewed. Four proximal variables were assessed: (a) quality of the caregiving environment, (b) family's regularity and predictability of daily routines, (c) caregiver's perception of the family's adequacy of resources, and (d) frequency and intensity of caregiver's experience with daily hassles. Results suggested that families of children enrolled in the center-based condition had more predictable daily routines than families of home-based participants. A family's adequacy of resources influenced the quality of the caregiving environment. Families with adequate resources were more likely to provide daily routines. Caregivers with fewer years of education were less able to establish and maintain daily routines which predicted, in part, a poorer caregiving environment.