The purpose of this study was to identify the perceptions of pre-service science teachers about using vee diagrams and preparing electronic portfolios in physics laboratuary course. 103 first grade pre-service science teachers who took general physics laboratuary course were the participants of the study. Pre-service teachers constructed vee diagrams for presenting their experiment reports and prepared electronic portfolios about whole laboratuary process. This research was based on case study design. Electronic portfolio composed of foreword, diaries and epilogue parts, open-ended questionnaire and semi-structured interviews composed of open-ended questions and holistic rubric prepared for grading vee diagrams of pre-service teachers were used as data sources. 12 pre-service teachers were selected purposefully by considering academic success and voluntariness for semi-structured interviews and document analyses of e-portfolios. Both descriptive and content analyses were used for analyzing data. The results show that pre-service teachers perceived that electronic portfolios and vee diagrams developed science process, metacognitive and social skills and identfying and preventing misconceptions.