The American Society of Biochemistry and Molecular Biology (ASBMB) has launched an National Science Foundation (NSF)-funded 5 year project to support biochemistry and molecular biology educators learning what and how students learn. As a part of this initiative, hundreds of life scientists will plan and develop a rich central resource for biochemistry and molecular biology educators. This resource will include identification of biochemistry and molecular biology core concepts, skills, assessment tools, and effective pedagogical approaches. As a first step in this endeavor, experts in life science education research and concept assessment development recently converged for a Concept Assessment in Biochemistry and Molecular Biology (CABMB) workshop on March 19-21, 2010 in Bethesda, Maryland. The first meeting marks the beginning of a project that hopes to involve hundreds of scientists and educators in biochemistry and molecular biology and closely related fields. ASBMB is calling on all educators and researchers in these fields to participate in this ambitious project.