The Coronavirus pandemic (COVID-19) has created a need for a workforce that interacts with the public every day to be educated on how to use personal protective equipment appropriately and practice CDC guided infection control procedures effectively in a very short amount of time. The individuals who make up a large portion of the workforce that occupy these essential positions typically do not have a college education. Educating adult learners has stark differences from educating children, and becomes more complex when working with underprepared and often, historically underserved populations who typically lack any level of formal, higher education experience. The online infection prevention course created by the Golisano Institute for Developmental Disability Nursing for Direct Support Professionals during COVID-19 was used as a case study to better understand the unique needs of adult learners with no formal college education and how to effectively meet those needs in a virtual, socially-distanced platform. It was identified that underprepared adult learners require their learning to be applicable to their current circumstances. Utilizing material that is condensed, and broken down into small portions of time, and the implementation of gaming elements showed greatest success in capturing student engagement and retention.