The 45th annual conference of the Adult and Higher Education Alliance (AHEA) was held virtually in March 2021. Papers in these proceedings include the following: (1) An Analysis of the Role of Communities of Practice in Transformational Learning during a Pandemic (Nighet Ahmed and Ava Tabb); (2) Using Children's Literature to Create a Culturally Responsive Teaching Environment in a Pre-Service Teacher Course (William Blackwell, Ashley B. Crane, and Christina M. Gushanas); (3) The Year the Planet Experienced a Transformative Learning Experience (Patricia G. Coberly-Holt and Megan Small); (4) Narrative and Valuing the Specific and Contextual in Experiential Learning (Abigail Dallmann); (5) Transformative Learning: Joining and Leaving a Cult (MaKenzie Douglas and Jeremy Schwehm); (6) Should College Educators Seek to Transform Their Students? (Alan Mandell and Xenia Coulter); (7) Learning Through Teaching: Self-transformation as a Result of COVID-19 (Katy Miller and Christina C. Wray); (8) Facing Moral Distress with Moral Courage in Nursing Education (Jessica H. Ochs); (9) Strategic Instruction and Educational Technology That Create Foundations for Change in Adult Students Learning Quantitative Concepts (Diane Perilli); (10) Impeding Transformative Learning: Combatting the Dunning-Kruger Effect (Megan L. Small and Patricia Holt); (11) The Nature and Function of CBO Systems of Support for Black Women at the Intersections of Trauma, Anxiety, Depression, and HIV/AIDS amid a Global Pandemic (Mattyna Stephens); (12) Academic Support on the Web: Graduate Student Use and Perceptions of Usefulness of Web Resources and Tools (Kelly Grieneisen Tillotson and Glenda A. Gunter); and (13) Reflexivity as a Catalyst to Transformational Learning: Creating Professionals for Volatile, Uncertain, Complex and Ambiguous Environments (Ruth Wylie and Robin McLaughlin). [For the 2020 proceedings, see ED606375.]