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Antonia Fruntke; Juliana Hu¨lsmann; Lennart Hendrik Skodda; Benedikt Blu¨mbott; Maren Godmann; Andreas Koschella; Thorsten Heinzel; Thomas Heinze; Timm Wilke – Journal of Chemical Education, 2025
The subject of pharmaceutical research has traditionally focused on drugs with systemic effects. However, contemporary approaches aspire to achieve targeted drug delivery, with the aim of combatting infections with a precise immune response. Active substances are encapsulated in nanoparticles, transported through the body, and selectively released…
Descriptors: Drug Therapy, Science Laboratories, Pharmacology, Chemistry
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Leonardo Antonelli; Rosiene Reis Mattos; Mauricio Moraes Victor; Silvio Cunha – Journal of Chemical Education, 2024
A multicomponent reaction was adapted and successfully applied in the major organic course, which involves synthesizing and characterizing a 1,3-benzoxazine derived from paracetamol extracted from tablets of the worldwide well-known medicine Tylenol. Using paracetamol as a reagent is a motivational strategy in undergraduate laboratories to meet…
Descriptors: Organic Chemistry, Medicine, Undergraduate Study, College Science
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Carmen Velez; Kristie Cheng; Sabrina Woodward; Noor Nazeer; Gabriela Nicole Hislop Gomez; Cody O. Crosby – Journal of Chemical Education, 2024
Many undergraduate chemistry and biochemistry students pursue careers in healthcare. Biomaterials, designed to harmonize with the complexity of the human body, have become increasingly significant in medicine as implants, drug delivery vehicles and tissue scaffolds. We believe it is essential that undergraduates are exposed to biomaterial…
Descriptors: Chemistry, Scientific Concepts, Medicine, College Science
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Mohamed Touaibia; Natalie A. Levesque – Journal of Chemical Education, 2024
Heterocycles, more specifically those containing nitrogen, make up a family of molecules with great pharmaceutical potential. Many approved drugs, notably anticancer drugs, contain a nitrogen-based heterocycle. To expose students to this class of molecules, we used the Paal--Knorr reaction for the synthesis of edaravone, a pyrazolone derivative.…
Descriptors: Chemistry, College Science, Undergraduate Students, Undergraduate Study