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Laura Caquelin; Pauline Badra; Lucas Poulain; Bruno Laviolle; Moreno Ursino; Clara Locher – Research Synthesis Methods, 2024
This study aimed to assess the feasibility of applying two recent phase I meta-analyses methods to protein kinase inhibitors (PKIs) developed in oncology and to identify situations where these methods could be both feasible and useful. This ancillary study used data from a systematic review conducted to identify dose-finding studies for PKIs. PKIs…
Descriptors: Oncology, Cancer, Medical Care Evaluation, Medical Research