Mediation analysis in Single Case Experimental Designs (SCEDs) evaluates intervention mechanisms for individuals. Despite recent methodological developments, no clear guidelines exist for maximizing power to detect the indirect effect in SCEDs. This study compares frequentist and Bayesian methods, determining (1) minimum required sample size to…

We have entered an era in which scientific evidence increasingly informs research practice and policy. As there is an exponential increase in the use of single-case experimental designs (SCEDs) to evaluate intervention effectiveness, there is accumulating evidence available for quantitative synthesis. Consequently, there is a growing interest in…