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Comparative Analysis2
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Simulation1
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Research Synthesis Methods2
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Dan Jackson2
Landan Zhang2
Sylwia Bujkiewicz1
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Four Alternative Methodologies for Simulated Treatment Comparison: How Could the Use of Simulation Be Re-Invigorated?
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Landan Zhang; Sylwia Bujkiewicz; Dan Jackson – Research Synthesis Methods, 2024
Simulated treatment comparison (STC) is an established method for performing population adjustment for the indirect comparison of two treatments, where individual patient data (IPD) are available for one trial but only aggregate level information is available for the other. The most commonly used method is what we call 'standard STC'. Here we fit…
Descriptors: Simulation, Patients, Outcomes of Treatment, Comparative Analysis
Generalizing Some Key Results from "Alternative Weighting Schemes When Performing Matching-Adjusted Indirect Comparisons"
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Landan Zhang; Dan Jackson – Research Synthesis Methods, 2024
A recent paper proposed an alternative weighting scheme when performing matching-adjusted indirect comparisons. This alternative approach follows the conventional one in matching the covariate means across two studies but differs in that it maximizes the effective sample size when doing so. The appendix of this paper showed, assuming there is one…
Descriptors: Comparative Analysis, Medical Research, Sample Size, Research Methodology