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Sayegh, Fares; Herraiz, Laurie; Colom, Morgane; Lopez, Sébastien; Rampon, Claire; Dahan, Lionel – Learning & Memory, 2022
Dopamine participates in encoding memories and could either encode rewarding/aversive value of unconditioned stimuli or act as a novelty signal triggering contextual learning. Here we show that intraperitoneal injection of the dopamine D1/5R antagonist SCH23390 impairs contextual fear conditioning and tone-shock association, while intrahippocampal…
Descriptors: Cognitive Processes, Memory, Fear, Conditioning
Yokose, Jun; Marks, William D.; Yamamoto, Naoki; Ogawa, Sachie K.; Kitamura, Takashi – Learning & Memory, 2021
Temporal association learning (TAL) allows for the linkage of distinct, nonsynchronous events across a period of time. This function is driven by neural interactions in the entorhinal cortical-hippocampal network, especially the neural input from the pyramidal cells in layer III of medial entorhinal cortex (MECIII) to hippocampal CA1 is crucial…
Descriptors: Associative Learning, Brain Hemisphere Functions, Neurological Organization, Stimuli
Cuartas, Jorge; Weissman, David G.; Sheridan, Margaret A.; Lengua, Liliana; McLaughlin, Katie A. – Child Development, 2021
Spanking remains common around the world, despite evidence linking corporal punishment to detrimental child outcomes. This study tested whether children (M[subscript age] = 11.60) who were spanked (N = 40) exhibited altered neural function in response to stimuli that suggest the presence of an environmental threat compared to children who were not…
Descriptors: Punishment, Child Development, Neurological Organization, Brain Hemisphere Functions