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Direct linkEscher, Jill; Yan, Wei; Rissman, Emilie F.; Wang, Hsiao-Lin V.; Hernandez, Arturo; Corces, Victor G. – Journal of Autism and Developmental Disorders, 2022
Investigations into the etiology of autism spectrum disorders have been largely confined to two realms: variations in DNA sequence and somatic developmental exposures. Here we suggest a third route--disruption of the germline epigenome induced by exogenous toxicants during a parent's gamete development. Similar to cases of germline mutation, these…
Descriptors: Etiology, Autism Spectrum Disorders, Genetics, Prenatal Influences
