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Brieger, Katharine K.; Bakulski, Kelly M.; Pearce, Celeste L.; Baylin, Ana; Dou, John F.; Feinberg, Jason I.; Croen, Lisa A.; Hertz-Picciotto, Irva; Newschaffer, Craig J.; Fallin, M. Daniele; Schmidt, Rebecca J. – Journal of Autism and Developmental Disorders, 2022
We examined maternal prenatal vitamin use or supplemental folic acid intake during month one of pregnancy for association with autism spectrum disorder (ASD) in the Early Autism Risk Longitudinal Investigation, an enriched-risk pregnancy cohort. Total folic acid intake was calculated from monthly prenatal vitamins, multivitamins, and other…
Descriptors: Prenatal Influences, Nutrition, Autism, Pervasive Developmental Disorders
Law, Mei L.; Singh, Jatinder; Mastroianni, Mathilde; Santosh, Paramala – Journal of Autism and Developmental Disorders, 2022
Prodromal symptoms of Autism Spectrum Disorder (ASD) have been detected within the first year of life. This review evaluated evidence from randomized controlled trials (RCTs) of parent-mediated interventions for infants under 24 months who are at risk for ASD. Electronic databases, including grey literature, were searched up till November 2019.…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Intervention
Horinouchi, Tomoko; Maeyama, Kaori; Nagai, Masashi; Mizobuchi, Masami; Takagi, Yasuko; Okada, Yuka; Kato, Takeshi; Nishimura, Mio; Kawasaki, Yoko; Yoshioka, Mieko; Takada, Satoshi; Matsumoto, Hisayuki; Nakamachi, Yuji; Saegusa, Jun; Fukushima, Sachiyo; Fujioka, Kazumichi; Tomioka, Kazumi; Nagase, Hiroaki; Nozu, Kandai; Iijima, Kazumoto; Nishimura, Noriyuki – Journal of Autism and Developmental Disorders, 2022
Neonatal jaundice has been suggested as a perinatal risk factor for autism spectrum disorder (ASD). We examined UGT1A1 polymorphisms to assess the potential of neonatal jaundice as a risk factor for ASD in children by using DNA extracted from preserved umbilical cord. In total, 79 children with ASD were genotyped for "UGT1A1*28"…
Descriptors: Neonates, Physiology, Biochemistry, Children
Radoeva, Petya D.; Ballinger, Kristen; Ho, Theodore; Webb, Sara J.; Stobbe, Gary A. – Journal of Autism and Developmental Disorders, 2022
Autistic individuals are at risk for developing depression though the risk and protective factors for co-occurring depression in autistic individuals are not yet fully characterized. In this retrospective medical chart review study, we explored factors associated with self-reported depressive symptoms (Patient Health Questionnaire-9) in autistic…
Descriptors: At Risk Persons, Depression (Psychology), Autism, Pervasive Developmental Disorders
Thapar, Anita; Rutter, Michael – Journal of Autism and Developmental Disorders, 2021
In the last 40 years, there has been a huge increase in autism genetics research and a rapidly growing number of discoveries. We now know autism is one of the most highly heritable disorders with negligible shared environmental contributions. Recent discoveries also show that rare variants of large effect size as well as small effect common gene…
Descriptors: Autism, Pervasive Developmental Disorders, Genetic Disorders, At Risk Persons
Parikh, Chandni; Iosif, Ana-Maria; Ozonoff, Sally – Journal of Autism and Developmental Disorders, 2021
Few studies have explored autism spectrum disorder (ASD) screening in the first year of life. The current investigation examines the psychometric properties of the Infant-Toddler Checklist starting in the first year of life in a sample at elevated and average risk for ASD based on family history. 283 participants were followed from 6 to 36 months,…
Descriptors: Autism, Pervasive Developmental Disorders, Screening Tests, Infants
Gibson, Louisa; Porter, Melanie – Journal of Autism and Developmental Disorders, 2022
Research has linked prenatal alcohol and tobacco use with Attention Deficit Hyperactivity Disorder (ADHD), and variably with Autism Spectrum Disorder (ASD). Lactational use has been scantly considered. This study examined whether it may alter ADHD or ASD risk. Participants were 5107 infants recruited in 2004 and assessed longitudinally for the…
Descriptors: Drinking, Smoking, Attention Deficit Hyperactivity Disorder, Autism
Van Rooijen, Rianne; Ward, Emma Kate; De Jonge, Maretha; Kemner, Chantal; Junge, Caroline – Journal of Child Language, 2022
Children diagnosed with autism spectrum disorder (ASD) often have smaller vocabularies in infancy compared to typically-developing children. To understand whether their smaller vocabularies stem from problems in learning, our study compared a prospective risk sample of 18 elevated risk and 11 lower risk 24-month-olds on current vocabulary size and…
Descriptors: Language Acquisition, Vocabulary Development, At Risk Persons, Autism
Santapuram, Pooja; Feldman, Jacob I.; Bowman, Sarah M.; Raj, Sweeya; Suzman, Evan; Crowley, Shannon; Kim, So Yoon; Keceli-Kaysili, Bahar; Bottema-Beutel, Kristen; Lewkowicz, David J.; Wallace, Mark T.; Woynaroski, Tiffany G. – Mind, Brain, and Education, 2022
Looking to the mouth of a talker early in life predicts expressive communication. We hypothesized that looking at a talker's mouth may signal that infants are ready for increased supported joint engagement and that it subsequently facilitates prelinguistic vocal development and translates to broader gains in expressive communication. We tested…
Descriptors: Infants, Expressive Language, Toddlers, Autism
Smith, Gillian S.; Fleming, Michael; Kinnear, Deborah; Henderson, Angela; Pell, Jill P.; Melville, Craig; Cooper, Sally-Ann – Autism: The International Journal of Research and Practice, 2021
Studies on children and adults combined suggest higher mortality rates for autistic than other people, but few report mortality rates for autistic children. In addition, past studies may not be representative of the current generation of children diagnosed with autism. We examined mortality in children using data from Scotland's annual pupil…
Descriptors: Death, Autism, Pervasive Developmental Disorders, Foreign Countries
Romeo, Rachel R.; Choi, Boin; Gabard-Durnam, Laurel J.; Wilkinson, Carol L.; Levin, April R.; Rowe, Meredith L.; Tager-Flusberg, Helen; Nelson, Charles A. – Journal of Autism and Developmental Disorders, 2022
In this study we investigated the impact of parental language input on language development and associated neuroscillatory patterns in toddlers at risk of Autism Spectrum Disorder (ASD). Forty-six mother-toddler dyads at either high (n = 22) or low (n = 24) familial risk of ASD completed a longitudinal, prospective study including free-play,…
Descriptors: Autism, Pervasive Developmental Disorders, Toddlers, At Risk Persons
Jokiranta-Olkoniemi, Elina; Gyllenberg, David; Sucksdorff, Dan; Suominen, Auli; Kronström, Kim; Chudal, Roshan; Sourander, Andre – Journal of Autism and Developmental Disorders, 2021
To examine the risk for premature mortality and intentional self-harm in autism spectrum disorders (ASD). Based on a national birth cohort. Children born in 1987-2005, diagnosed with ASD by 2007 (n = 4695) were matched with four non-ASD subjects (n = 18,450) and followed until 2015 for mortality and intentional self-harm. The risk among ASD…
Descriptors: Death, Intention, Self Destructive Behavior, Autism
LaBianca, Sonja; LaBianca, Jette; Pagsberg, Anne Katrine; Jakobsen, Klaus Damgaard; Appadurai, Vivek; Buil, Alfonso; Werge, Thomas – Journal of Autism and Developmental Disorders, 2021
Autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) are highly heritable neurodevelopmental disorders that frequently co-occur. Both rare and common genetic variants are important for ASD and ADHD risk but their combined contribution to clinical heterogeneity is unclear. In a sample of 39 ASD and/or ADHD families we…
Descriptors: Autism, Pervasive Developmental Disorders, Attention Deficit Hyperactivity Disorder, Comorbidity
Godoy, Priscilla B. G.; Shephard, Elizabeth; Milosavljevic, Bosiljka; Johnson, Mark H.; Charman, Tony – Journal of Autism and Developmental Disorders, 2021
Shared difficulties with cognitive control may play a role in co-occurring mental health problems frequently observed in autistic children. We investigated how different cognitive control processes (inhibitory control, conflict resolution, cognitive flexibility) associated with traits of autism spectrum disorder (ASD),…
Descriptors: Children, Autism, Pervasive Developmental Disorders, Attention Deficit Hyperactivity Disorder
Konke, Linn Andersson; Forslund, Tommie; Nilsson-Jobs, Elisabeth; Nyström, Pär; Falck-Ytter, Terje; Brocki, Karin – Journal of Autism and Developmental Disorders, 2022
The current study investigated longitudinal associations between parent-rated temperament, observed exuberance and accelerometer activity level at 18-months and symptoms of ASD and ADHD at 36-months in a sample of 54 children at elevated likelihood for ASD. For the specific parent-rated temperament scales, most observed significant associations…
Descriptors: Personality Traits, Toddlers, Autism, Pervasive Developmental Disorders