Objectives: Characterise the circumstances associated with death during admission of adults with Down syndrome (DS) and to identify predictors of mortality. Patients and Methods: Observational study based on data on all emergent admissions of adults with DS to hospitals of the Spanish National Health System between 1997 and 2014. We analysed…

Background: Recent evidence suggests that speech substantially changes in ageing. As a complex neurophysiological process, it can accurately reflect changes in the motor and cognitive systems underpinning human speech. Since healthy ageing is not always easily discriminable from early stages of dementia based on cognitive and behavioural…

Behaviour change communication (BCC) remains a central component of the interventions used in the fight against malaria in Ghana. However, there is limited evidence of its effectiveness. This study evaluated the effects of BCC strategies on knowledge (symptoms, causes and prevention) and overall knowledge of malaria among Ghanaian women aged…

Encephalitis is a clinical syndrome which can include altered mental status, motor and sensory deficits, altered behavior including personality changes, speech and movement disorders and seizures. While the overall incidence of encephalitis is not known, it is common enough that most pediatric and adolescent medicine physicians will have seen at…

Purpose: Americans with rheumatoid arthritis (RA) represent an emerging vocational rehabilitation (VR) clientele. Method: Following an overview of the etiology, incidence, prevalence, and impact of RA, the authors present strategies to meet the service and support needs of Americans with RA across the phases of the VR process. Results: The…

Purpose: This paper aimed to examine the sources of information and use of personal protective equipment (PPE) during the COVID-19 pandemic in the province of Punjab, Pakistan. The COVID-19 pandemic affected at a large level of all social institutions including the healthcare system of the countries. Design/methodology/approach: The study was…

Background: Pathologic aerophagia (PA) is characterised by excessive swallowing of air resulting in significant abdominal distension or belching. This is a relatively rare condition in general population but has been reported in up to 8.8% of institutionalised patients with intellectual disability. In severe cases, this can cause volvulus and…

By highlighting the critical thinking that (1) analyzes and evaluates arguments for claims about vaccinations and autism, and (2) engages in a form of methodological skepticism that systematically and continuously asks Critical Questions, a philosophical approach is introduced to deal directly and systematically with students' (and publicly…

Background: Death of people with intellectual disabilities is considered to be earlier than for the general population. Methods: Databases were searched for key words on intellectual disabilities and death. Strict inclusion/exclusion criteria were used. Information was extracted from selected papers, tabulated and synthesized. Prospero…

Purpose: Vocal fold diseases affecting the epithelium have a detrimental impact on vocal function. This review article provides an overview of apoptosis, the most commonly studied type of programmed cell death. Because apoptosis can damage epithelial cells, this article examines the implications of apoptosis on diseases affecting the vocal fold…

In this article, Marianne Cutler and Liz Lawrence describe in more detail the opportunities for "working scientifically" provided by this new Association for Science Education (ASE) resource, which was introduced in the previous issue, along with some of the feedback from teachers who have trialled the resources. [This article was…

At the examination of a patient, a doctor evaluates clinical picture of the disease that manifests itself by a great number of various general and local symptoms caused by an etiological factor and pathogenesis changes of the different organs and systems of the organism. A purpose of the surgical patient examination is making of early, correct and…

Lung cancer is the second most common cancer diagnosis and is the leading cause of cancer-related death in the United States for both men and women. The etiologies of many different types of lung cancer can be linked to risk factors that can be prevented, such as chronic tobacco smoking. Lung cancer is significantly more prevalent among…

The aim of this retrospective study, with prospective data collection, was to correlate congenital cytomegalovirus (CMV) infection with autism spectrum disorder (ASD) and to define its prevalence. Seventy proven congenitally-infected infants, born between 2007 and 2012, were referred to our centre for CMV diagnosis and follow-up, which consisted…

Objective: This study investigated how older adults' representations of hypertension relate to their illness experience (years of illness), health literacy and self-rated health. Design: Correlational study. Setting: Community-based older adults diagnosed with hypertension. Method: We measured health literacy (Short Test of Functional Health…