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Positive Feedback Relationship between Lipid Peroxidation and Amyloidogenesis Offers Insights into the Pathogenesis of Alzheimer's Disease
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Paddock, Brie; Davenport, Caty – HAPS Educator, 2017
Alzheimer's disease is a progressive neurodegenerative disorder characterized by amyloid plaques, synapse dysfunction, and memory loss. The production and accumulation of A[beta] peptides, a major component of the amyloid plaques, is sensitive to many genetic and environmental factors. Recently, research has focused on the role of oxidative stress…
Descriptors: Alzheimers Disease, Physiology, Anatomy, Neurology