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Michela Tinelli M; Aine Roddy; Martin Knapp; Celso Arango; Maria Andreina Mendez; James Cusack; Declan Murphy; Roberto Canitano; Bethany Oakley; Vinciane Quoidbach – Journal of Autism and Developmental Disorders, 2024
We examine the cost-effectiveness of treating epilepsy with anti-epileptic medicines in autistic children, looking at impacts on healthcare providers (in England, Ireland, Italy and Spain) and children's families (in Ireland). We find carbamazepine to be the most cost-effective drug to try first in children with newly diagnosed focal seizures. For…
Descriptors: Foreign Countries, Autism Spectrum Disorders, Epilepsy, Pharmacology
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Holmes, Eileen M.; Leahy, Joy; Walsh, Cathal D.; White, Arthur; Donnan, Peter T.; Lamrock, Felicity – Research Synthesis Methods, 2019
Indirect treatment comparisons are useful to estimate relative treatment effects when head-to-head studies are not conducted. Statisticians at the National Centre for Pharmacoeconomics Ireland (NCPE) and Scottish Medicines Consortium (SMC) assess the clinical and cost-effectiveness of new medicines as part of multidisciplinary teams. We describe…
Descriptors: Decision Making, Drug Therapy, Comparative Analysis, Pharmacology