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Direct linkSandra Jensen-Willett; Andrea Cunha; Michele A. Lobo; Regina Harbourne; Stacey C. Dusing; Sarah W. McCoy; Natalie A. Koziol; Lin-Ya Hsu; Emily C. Marcinowski; Iryna Babik; Mihee An; James A. Bovaird – Grantee Submission, 2022
Purpose: This case series documents developmental changes over time and in response to a novel intervention, Sitting Together and Reaching to Play (START-Play), in children with early-life seizures. Methods: Thirteen children with early-life seizures were included from a subset of participants in the START-Play multisite, randomized controlled…
Descriptors: Seizures, Cognitive Development, Motor Development, Child Development
Phillip Forman; Edward Khokhlovich; Andrey Vyshedskiy – Journal of Developmental and Physical Disabilities, 2023
The effect associated with the presence of seizures in 2 to 5-year-old autistic children was investigated in the largest and the longest observational study to-date. Parents assessed the development of 8461 children quarterly for three years on five orthogonal subscales: combinatorial receptive language, expressive language, sociability, sensory…
Descriptors: Longitudinal Studies, Young Children, Autism Spectrum Disorders, Seizures
Baram, Tallie Z.; Donato, Flavio; Holmes, Gregory L. – Learning & Memory, 2019
Spatial memory, the aspect of memory involving encoding and retrieval of information regarding one's environment and spatial orientation, is a complex biological function incorporating multiple neuronal networks. Hippocampus-dependent spatial memory is not innate and emerges during development in both humans and rodents. In children,…
Descriptors: Memory, Spatial Ability, Cognitive Processes, Neurological Organization
Uzun Cicek, Ayla; Sari, Seda Aybuke; Mercan Isik, Cansu – Journal of Mental Health Research in Intellectual Disabilities, 2020
Introduction: Intellectual disability (ID) is characterized by limitations in cognitive and adaptive functioning. The aim of this study is to examine sociodemographic characteristics, perinatal and childhood risk factors, and prevalence of psychiatric and biomedical comorbidities in children with ID. Methods: 260 patients with ID were included in…
Descriptors: Risk, Incidence, Case Studies, Comorbidity
Peters, S. U.; Hundley, R. J.; Wilson, A. K.; Carvalho, C. M. B.; Lupski, J. R.; Ramocki, M. B. – Journal of Autism and Developmental Disorders, 2013
The aim of this study was to determine the frequency, timing, and associated features of developmental regression in "MECP2" duplication syndrome. We also examined whether duplication size was associated with regression. Comprehensive psychological evaluations were used to assess 17 boys with "MECP2" duplication syndrome.…
Descriptors: Genetic Disorders, Males, Child Development, Language Skills
Jones, Kyle B.; Cottle, Kristina; Bakian, Amanda; Farley, Megan; Bilder, Deborah; Coon, Hilary; McMahon, William M. – Autism: The International Journal of Research and Practice, 2016
This study describes medical conditions experienced by a population-based cohort of adults with autism spectrum disorder whose significant developmental concerns were apparent during childhood. As part of a 25-year outcome study of autism spectrum disorder in adulthood, medical histories were collected on 92 participants (N = 69 males) who were…
Descriptors: Adults, Autism, Pervasive Developmental Disorders, Developmental Disabilities
Brashear, Allison; Mink, Jonathan W.; Hill, Deborah F.; Boggs, Niki; McCall, W. Vaughn; Stacy, Mark A.; Snively, Beverly; Light, Laney S.; Sweadner, Kathleen J.; Ozelius, Laurie J.; Morrison, Leslie – Developmental Medicine & Child Neurology, 2012
We report new clinical features of delayed motor development, hypotonia, and ataxia in two young children with mutations (R756H and D923N) in the "ATP1A3" gene. In adults, mutations in "ATP1A3" cause rapid-onset dystonia-Parkinsonism (RDP, DYT12) with abrupt onset of fixed dystonia. The parents and children were examined and videotaped, and…
Descriptors: Athletes, Sports Medicine, Motor Development, Seizures
Strekas, Amy; Ratner, Nan Bernstein; Berl, Madison; Gaillard, William D. – International Journal of Language & Communication Disorders, 2013
Background: There is a noticeable publication gap in the speech-language pathology literature regarding the language abilities of children with common types of epilepsy. This paper reviews studies that suggest a high frequency of undetected language problems in this population, and it proposes the need for pragmatically based assessment of…
Descriptors: Epilepsy, Children, Language Skills, Language Impairments
Visser, Annemarie M.; Jaddoe, Vincent W. V.; Ghassabian, Akhgar; Schenk, Jacqueline J.; Verhulst, Frank C.; Hofman, Albert; Tiemeier, Henning; Moll, Henriette A.; Arts, Willem Frans M. – Developmental Medicine & Child Neurology, 2012
Aim: General developmental outcome is known to be good in school-aged children who experienced febrile seizures. We examined cognitive and behavioural outcomes in preschool children with febrile seizures, including language and executive functioning outcomes. Method: This work was performed in the Generation R Study, a population-based cohort…
Descriptors: Behavior Problems, Child Behavior, Expressive Language, Language Acquisition
Bok, Levinus A.; Halbertsma, Feico J..; Houterman, Saskia; Wevers, Ron A.; Vreeswijk, Charlotte; Jakobs, Cornelis; Struys, Eduard; van der Hoeven, Johan H.; Sival, Deborah A.; Willemsen, Michel A. – Developmental Medicine & Child Neurology, 2012
Aim: The long-term outcome of the Dutch pyridoxine-dependent epilepsy cohort and correlations between patient characteristics and follow-up data were retrospectively studied. Method: Fourteen patients recruited from a national reference laboratory were included (four males, 10 females, from 11 families; median age at assessment 6y; range 2y…
Descriptors: Epilepsy, Seizures, At Risk Persons, Cognitive Development
Horovitz, Max; Matson, Johnny L. – Research in Developmental Disabilities: A Multidisciplinary Journal, 2011
The attainment of developmental milestones was examined and compared in 162 infants and toddlers with developmental disabilities, including Down Syndrome (n = 26), Cerebral Palsy (n = 19), Global Developmental Delay (n = 22), Premature birth (n = 66), and Seizure Disorder (n = 29). Toddlers in the Seizures Disorder group began crawling at a…
Descriptors: Physical Activities, Seizures, Developmental Disabilities, Down Syndrome
National Dissemination Center for Children with Disabilities, 2010
Epilepsy is a seizure disorder. According to the Epilepsy Foundation of America, a seizure happens when a brief, strong surge of electrical activity affects part or all of the brain. About three million Americans have epilepsy. Of the 200,000 new cases diagnosed each year, nearly 45,000 are children and adolescents. Following a brief story of a…
Descriptors: Epilepsy, Seizures, Children, Adolescents
Reilly, Colin J. – Research in Developmental Disabilities: A Multidisciplinary Journal, 2011
ADHD and epilepsy common are both common childhood disorders and both can have significant negative consequences on a child's behavioural, learning, and social development. Both conditions can co-occur and population studies suggest that the prevalence of ADHD in childhood epilepsy is between 12 and 17%. The prevalence of epilepsy in ADHD is lower…
Descriptors: Epilepsy, Incidence, Mental Retardation, Quality of Life
Prenatal Stress and Risk of Febrile Seizures in Children: A Nationwide Longitudinal Study in Denmark
Li, Jiong; Olsen, Jorn; Obel, Carsten; Christensen, Jakob; Precht, Dorthe Hansen; Vestergaard, Mogens – Journal of Autism and Developmental Disorders, 2009
We aimed to examine whether exposure to prenatal stress following maternal bereavement is associated with an increased risk of febrile seizures. In a longitudinal population-based cohort study, we followed 1,431,175 children born in Denmark. A total of 34,777 children were born to women who lost a close relative during pregnancy or within 1 year…
Descriptors: Grief, Seizures, Pregnancy, Foreign Countries
Scheffer, Ingrid E.; Turner, Samantha J.; Dibbens, Leanne M.; Bayly, Marta A.; Friend, Kathryn; Hodgson, Bree; Burrows, Linda; Shaw, Marie; Wei, Chen; Ullmann, Reinhard; Ropers, Hans-Hilger; Szepetowski, Pierre; Haan, Eric; Mazarib, Aziz; Afawi, Zaid; Neufeld, Miriam Y.; Andrews, P. Ian; Wallace, Geoffrey; Kivity, Sara; Lev, Dorit; Lerman-Sagie, Tally; Derry, Christopher P.; Korczyn, Amos D.; Gecz, Jozef; Mulley, John C.; Berkovic, Samuel F. – Brain, 2008
Epilepsy and Mental Retardation limited to Females (EFMR) which links to Xq22 has been reported in only one family. We aimed to determine if there was a distinctive phenotype that would enhance recognition of this disorder. We ascertained four unrelated families (two Australian, two Israeli) where seizures in females were transmitted through…
Descriptors: Epilepsy, Mental Retardation, Females, Genetics
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