It is well documented that implementing biosecurity on an animal farm is beneficial to the animal's health and wellness and in reducing the risk of production losses caused by diseases. However, compliance of biosecurity protocols has been shown to be low, and a lack of training has been blamed. A preliminary Systems Thinking model is presented to…

Histone acetylation, catalyzed by e, has emerged as a promising therapeutic strategy in Alzheimer's disease (AD). By longitudinally characterizing spatial memory at 3, 6, and 9 mo of age, we show that acute activation and inhibition of the histone acetyltransferase PCAF remediated memory impairments in 3xTG-AD mice in an age-related bidirectional…

Purpose: The larynx is a uniquely situated organ, juxtaposed between the gastrointestinal and respiratory tracts, and endures considerable immunological challenges while providing reflexogenic responses via putative mucosal mechanoreceptor afferents. Laryngeal afferents mediate precise monitoring of sensory events by relay to the internal branch…

Humans are living in damaged landscapes within a new geographical epoch known as the Anthropocene. The COVID-19 outbreak fuels uncertainty, instability, and ambiguity for humans. This viral disaster has been blamed for losing and further exacerbating ecological imbalance, and prompts a need to re-examine multispecies relations and, in particular,…

Using a hippocampus-dependent contextual threat learning and memory task, we report widespread, coordinated DNA methylation changes in CA1 hippocampus of Sprague-Dawley rats specific to threat learning at genes involved in synaptic transmission. Experience-dependent alternations in gene expression and DNA methylation were observed as early as 1 h…

Largely inspired from clinical concepts like brain reserve, cognitive reserve, and neural compensation, here we review data showing how neural circuits reorganize in presymptomatic and early symptomatic hAPP mice to maintain memory intact. By informing on molecular alterations and compensatory adaptations which take place in the brain before mice…

Individual differences in cognitive decline during normal aging and Alzheimer's disease (AD) are common, but the molecular mechanisms underlying these distinct outcomes are not fully understood. We utilized a combination of genetic, molecular, and behavioral data from a mouse population designed to model human variation in cognitive outcomes to…

Spatial working memory (SWM) is the ability to encode, maintain, and retrieve spatial information over a temporal gap, and relies on a network of structures including the medial septum (MS), which provides critical input to the hippocampus. Although the role of the MS in SWM is well-established, up until recently, we have been unable to use…

On-farm bacteriologic culturing (OFBC) provides quick and inexpensive mastitis diagnosis, but commercial adoption of this innovation has been low in Mississippi. We implemented an Extension-led trialing program to identify reasons for producers' lack of OFBC adoption, explore change in producers' knowledge and perceptions of OFBC, and assess the…

This chapter explores the urgent relevance of posthumanist theory and practice for democratizing creative educational experiences in 21st-century schools, universities, and informal learning environments. Posthumanism challenges the myopic centering of the human in creative education in an age of climate change, artificial intelligence, and…

The world is changing: both a conventional and a vaccine passport are now needed to travel internationally. Mask mandates, and social distancing are the new norm in a rapidly changing society. These measures were put in place to control the spread of the highly infectious and often fatal COVID-19, caused by a viral agent, a microorganism, a…

We examined risk perceptions that aquatic-based recreation stakeholders in the Great Lakes region held about fish diseases, using viral hemorrhagic septicemia (VHS) as our case study. Eighty-five percent of study participants knew nothing or very little about VHS. Regarding risks posed by VHS, participants overall were most concerned about risks…

Science popularisation festivals attract more and more people every year, showing that there is a need to satisfy public curiosity. Such events are good occasions to disseminate knowledge to a large audience. The results of scientific research bring advances for mankind. Since research mostly depends on public funds, it is important to gain…

Bovine respiratory disease (BRD) is an often unrecognized problem in cow-calf herds. We describe a program we used to help producers identify and avoid practices that could increase their herds' risk for BRD. The greatest knowledge gains occurred for the topics of costs associated with BRD, BRD risks at the feedlot, and biosecurity measures.…

Research has shown that animal-assisted activities have specific benefits for older adults, such as decreasing loneliness (Banks & Banks, 2002; Banks, Willoughby, & Banks, 2008; Calvert, 1989) and depression (Grubbs, Artese, Schmitt, Cormier, & Panton, 2016; Le Roux & Kemp, 2009; Moretti et al., 2010) while increasing positive…