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Infant Vocalizing and Phenotypic Outcomes in Autism: Evidence from the First 2 Years
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Plate, Samantha; Yankowitz, Lisa; Resorla, Leslie; Swanson, Meghan R.; Meera, Shoba Sreenath; Estes, Annette; Marrus, Natasha; Cola, Meredith; Petrulla, Victoria; Faggen, Aubrey; Pandey, Juhi; Paterson, Sarah; Pruett, John R., Jr.; Hazlett, Heather; Dager, Stephen; St. John, Tanya; Botteron, Kelly; Zwaigenbaum, Lonnie; Piven, Joseph; Schultz, Robert T.; Parish-Morris, Julia – Child Development, 2022
Infant vocalizations are early-emerging communicative markers shown to be atypical in autism spectrum disorder (ASD), but few longitudinal, prospective studies exist. In this study, 23,850 infant vocalizations from infants at low (LR)- and high (HR)-risk for ASD (HR-ASD = 23, female = 3; HR-Neg = 35, female = 13; LR = 32, female = 10; 80% White;…
Descriptors: Infants, Toddlers, Verbal Communication, Autism
Assessment of Autism Symptoms from 6 to 18 Months of Age Using the Autism Observation Scale for Infants in a Prospective High-Risk Cohort
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Zwaigenbaum, Lonnie; Bryson, Susan E.; Brian, Jessica; Smith, Isabel M.; Sacrey, Lori; Armstrong, Vickie; Roberts, Wendy; Szatmari, Peter; Garon, Nancy; Vaillancourt, Tracy; Roncadin, Caroline – Child Development, 2021
The objectives were to characterize behavioral signs of autism spectrum disorder (ASD) in younger siblings of diagnosed children (high-risk; HR) and examine classification features of the Autism Observation Scale for Infants (AOSI). Participants (501 HR and 180 low-risk [LR]) were assessed between 6 and 18 months using the AOSI and at age 3 for…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Infant Behavior
The Autism Parent Screen for Infants: Predicting Risk of Autism Spectrum Disorder Based on Parent-Reported Behavior Observed at 6-24 Months of Age
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Sacrey, Lori-Ann R.; Bryson, Susan; Zwaigenbaum, Lonnie; Brian, Jessica; Smith, Isabel M.; Roberts, Wendy; Szatmari, Peter; Vaillancourt, Tracy; Roncadin, Caroline; Garon, Nancy – Autism: The International Journal of Research and Practice, 2018
This study examined whether a novel parent-report questionnaire, the Autism Parent Screen for Infants, could differentiate infants subsequently diagnosed with autism spectrum disorder from a high-risk cohort (siblings of children diagnosed with autism spectrum disorder (n = 66)) from high-risk and low-risk comparison infants (no family history of…
Descriptors: Autism, Infants, Pervasive Developmental Disorders, Parents
Potential Risk Factors for the Development of Self-Injurious Behavior among Infants at Risk for Autism Spectrum Disorder
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Dimian, Adele F.; Botteron, Kelly N.; Dager, Stephen R.; Elison, Jed T.; Estes, Annette M.; Pruett, John R., Jr.; Schultz, Robert T.; Zwaigenbaum, Lonnie; Piven, Joseph; Wolff, Jason J. – Journal of Autism and Developmental Disorders, 2017
Prevalence of self-injurious behavior (SIB) is as high as 50% among children with autism spectrum disorder (ASD). Identification of risk factors for the development of SIB is critical to early intervention and prevention. However, there is little empirical research utilizing a prospective design to identify early risk factors for SIB. The purpose…
Descriptors: Risk, Self Destructive Behavior, Autism, Pervasive Developmental Disorders
Studying the Emergence of Autism Spectrum Disorders in High-Risk Infants: Methodological and Practical Issues
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Zwaigenbaum, Lonnie; Thurm, Audrey; Stone, Wendy; Baranek, Grace; Bryson, Susan; Iverson, Jana; Kau, Alice; Klin, Ami; Lord, Cathy; Landa, Rebecca; Rogers, Sally; Sigman, Marian – Journal of Autism and Developmental Disorders, 2007
Detecting early signs of autism is essential for timely diagnosis and initiation of effective interventions. Several research groups have initiated prospective studies of high-risk populations including infant siblings, to systematically collect data on early signs within a longitudinal design. Despite the potential advantages of prospective…
Descriptors: Infants, Siblings, Autism, At Risk Persons