NotesFAQContact Us
Collection
Advanced
Search Tips
Showing all 13 results Save | Export
The Importance of Temperament for Understanding Early Manifestations of Autism Spectrum Disorder in High-Risk Infants
Peer reviewed Peer reviewed
Direct linkDirect link
Paterson, Sarah J.; Wolff, Jason J.; Elison, Jed T.; Winder-Patel, Breanna; Zwaigenbaum, Lonnie; Estes, Annette; Pandey, Juhi; Schultz, Robert T.; Botteron, Kelly; Dager, Stephen R.; Hazlett, Heather C.; Piven, Joseph; Piven, J.; Hazlett, H. C.; Chappell, C.; Dager, S.; Estes, A.; Shaw, D.; Botteron, K. N.; McKinstry, R. C.; Constantino, J.; Pruett, J.; Schultz, R. T.; Paterson, S.; Zwaigenbaum, L.; Elison, J.; Evans, A. C.; Collins, D. L.; Pike, G. B.; Fonov, V.; Kostopoulos, P.; Das, S.; Gerig, G.; Styner, M.; Gu, H. – Journal of Autism and Developmental Disorders, 2019
The present study investigated the relationship between infant temperament characteristics and autism spectrum disorder (ASD) risk status. Temperament was examined at 6, 12, and 24 months in 282 infants at high familial risk for ASD and 114 low-risk controls using the Infant Behavior Questionnaire-Revised and Early Childhood Behavior…
Descriptors: Autism, Pervasive Developmental Disorders, Infants, At Risk Persons
Screening for Behavioral Signs of Autism Spectrum Disorder in 9-Month-Old Infant Siblings
Peer reviewed Peer reviewed
Direct linkDirect link
Sacrey, Lori-Ann R.; Zwaigenbaum, Lonnie; Bryson, Susan; Brian, Jessica; Smith, Isabel M.; Roberts, Wendy; Szatmari, Peter; Vaillancourt, Tracy; Roncadin, Caroline; Garon, Nancy – Journal of Autism and Developmental Disorders, 2021
Despite considerable progress in characterizing the early signs of autism spectrum disorder (ASD), more remains to be learned about how symptoms emerge in the first year of life. Parents with a new baby who already had at least one biological child diagnosed with ASD (high-risk) or no family history of ASD (low-risk) completed two measures when…
Descriptors: Siblings, Screening Tests, Autism, Pervasive Developmental Disorders
Assessment of Autism Symptoms from 6 to 18 Months of Age Using the Autism Observation Scale for Infants in a Prospective High-Risk Cohort
Peer reviewed Peer reviewed
Direct linkDirect link
Zwaigenbaum, Lonnie; Bryson, Susan E.; Brian, Jessica; Smith, Isabel M.; Sacrey, Lori; Armstrong, Vickie; Roberts, Wendy; Szatmari, Peter; Garon, Nancy; Vaillancourt, Tracy; Roncadin, Caroline – Child Development, 2021
The objectives were to characterize behavioral signs of autism spectrum disorder (ASD) in younger siblings of diagnosed children (high-risk; HR) and examine classification features of the Autism Observation Scale for Infants (AOSI). Participants (501 HR and 180 low-risk [LR]) were assessed between 6 and 18 months using the AOSI and at age 3 for…
Descriptors: Autism, Pervasive Developmental Disorders, Symptoms (Individual Disorders), Infant Behavior
Precursors of Self-Regulation in Infants at Elevated Likelihood for Autism Spectrum Disorder
Peer reviewed Peer reviewed
Direct linkDirect link
Garon, Nancy; Zwaigenbaum, Lonnie; Bryson, Susan E.; Smith, Isabel M.; Brian, Jessica; Roncadin, Caroline; Vaillancourt, Tracy; Armstrong, Vickie L.; Sacrey, Lori-Ann R.; Roberts, Wendy – Developmental Science, 2022
Research concerning temperament in children and adults with autism spectrum disorder (ASD) has suggested a consistent profile of low positive affect, high negative affect, and low regulation (Visser et al., 2016). One area receiving less attention is individual differences among children diagnosed with ASD. The primary objective of this study was…
Descriptors: Self Control, Infants, Autism Spectrum Disorders, Individual Differences
The Performance of the First Year Inventory (FYI) Screening on a Sample of High-Risk 12-Month-Olds Diagnosed with Autism Spectrum Disorder (ASD) at 36 Months
Peer reviewed Peer reviewed
Direct linkDirect link
Lee, Helen Y.; Vigen, Cheryl; Zwaigenbaum, Lonnie; Bryson, Susan; Smith, Isabel; Brian, Jessica; Watson, Linda R.; Crais, Elizabeth R.; Turner-Brown, Lauren; Reznick, J. Steven; Baranek, Grace T. – Journal of Autism and Developmental Disorders, 2019
This study examined the performance of the First Year Inventory (FYI; version 2.0), a community-normed parent-reported screening instrument, in a high-risk (HR) sample of 12-month-olds with older siblings diagnosed with autism spectrum disorder (ASD). The FYI 2.0 was completed by parents of 86 HR infants and 35 low-risk control infants at age…
Descriptors: Toddlers, Screening Tests, At Risk Persons, Autism
Construct Validity of the First-Year Inventory (FYI Version 2.0) in 12-Month-Olds at High-Risk for Autism Spectrum Disorder
Peer reviewed Peer reviewed
Direct linkDirect link
Lee, Helen Y.; Vigen, Cheryl; Zwaigenbaum, Lonnie; Smith, Isabel M.; Brian, Jessica; Watson, Linda R.; Crais, Elizabeth R.; Baranek, Grace T. – Autism: The International Journal of Research and Practice, 2021
This study examines the construct validity of the First-Year Inventory 2.0 with respect to other established instruments in a sample of high-risk infant siblings of children with Autism Spectrum Disorder. The First-Year Inventory 2.0 is a parent-report screening instrument designed to identify 12-month-old infants at risk for an eventual diagnosis…
Descriptors: Test Validity, Construct Validity, Autism, Pervasive Developmental Disorders
Brief Report: Assessment of Early Sensory Processing in Infants at High-Risk of Autism Spectrum Disorder
Peer reviewed Peer reviewed
Direct linkDirect link
Germani, Tamara; Zwaigenbaum, Lonnie; Bryson, Susan; Brian, Jessica; Smith, Isabel; Roberts, Wendy; Szatmari, Peter; Roncadin, Caroline; Sacrey, Lori Ann R.; Garon, Nancy; Vaillancourt, Tracy – Journal of Autism and Developmental Disorders, 2014
This study assessed sensory processing differences between 24-month infants at high-risk of autism spectrum disorder (ASD), each with an older sibling with ASD, and low-risk infants with no family history of ASD. Sensory processing differences were assessed using the Infant/Toddler Sensory Profile, a parent-reported measure. Groups were compared…
Descriptors: Pervasive Developmental Disorders, Autism, Siblings, Infants
The Autism Parent Screen for Infants: Predicting Risk of Autism Spectrum Disorder Based on Parent-Reported Behavior Observed at 6-24 Months of Age
Peer reviewed Peer reviewed
Direct linkDirect link
Sacrey, Lori-Ann R.; Bryson, Susan; Zwaigenbaum, Lonnie; Brian, Jessica; Smith, Isabel M.; Roberts, Wendy; Szatmari, Peter; Vaillancourt, Tracy; Roncadin, Caroline; Garon, Nancy – Autism: The International Journal of Research and Practice, 2018
This study examined whether a novel parent-report questionnaire, the Autism Parent Screen for Infants, could differentiate infants subsequently diagnosed with autism spectrum disorder from a high-risk cohort (siblings of children diagnosed with autism spectrum disorder (n = 66)) from high-risk and low-risk comparison infants (no family history of…
Descriptors: Autism, Infants, Pervasive Developmental Disorders, Parents
Beyond Autism: A Baby Siblings Research Consortium Study of High-Risk Children at Three Years of Age
Peer reviewed Peer reviewed
Direct linkDirect link
Messinger, Daniel; Young, Gregory S.; Ozonoff, Sally; Dobkins, Karen; Carter, Alice; Zwaigenbaum, Lonnie; Landa, Rebecca J.; Charman, Tony; Stone, Wendy L.; Constantino, John N.; Hutman, Ted; Carver, Leslie J.; Bryson, Susan; Iverson, Jana M.; Strauss, Mark S.; Rogers, Sally J.; Sigman, Marian – Journal of the American Academy of Child & Adolescent Psychiatry, 2013
Objective: First-degree relatives of persons with an autism spectrum disorder (ASD) are at increased risk for ASD-related characteristics. As little is known about the early expression of these characteristics, this study characterizes the non-ASD outcomes of 3-year-old high-risk (HR) siblings of children with ASD. Method: Two groups of children…
Descriptors: Outcome Measures, Autism, Early Intervention, Siblings
The Autism Observation Scale for Infants: Scale Development and Reliability Data
Peer reviewed Peer reviewed
Direct linkDirect link
Bryson, Susan E.; Zwaigenbaum, Lonnie; Mcdermott, Catherine; Rombough, Vicki; Brian, Jessica – Journal of Autism and Developmental Disorders, 2008
The Autism Observation Scale for Infants (AOSI) was developed to detect and monitor early signs of autism as they emerge in high-risk infants (all with an older sibling with an autistic spectrum disorder). Here we describe the scale and its development, and provide preliminary data on its reliability. Inter-rater reliability both for total scores…
Descriptors: Observation, Autism, Interrater Reliability, Infants
Temperament and Its Relationship to Autistic Symptoms in a High-Risk Infant Sib Cohort
Peer reviewed Peer reviewed
Direct linkDirect link
Garon, Nancy; Bryson, Susan E.; Zwaigenbaum, Lonnie; Smith, Isabel M.; Brian, Jessica; Roberts, Wendy; Szatmari, Peter – Journal of Abnormal Child Psychology, 2009
The present study prospectively investigated early temperamental profiles and their associations with autistic symptoms in high-risk infants (N = 138) with an older sibling with autistic spectrum disorder (ASD) and low-risk infants (N = 73) with no family history of ASD. Children who were diagnosed with ASD at 36 months were distinguished from…
Descriptors: Intelligence Quotient, Infants, Personality Traits, Symptoms (Individual Disorders)
Studying the Emergence of Autism Spectrum Disorders in High-Risk Infants: Methodological and Practical Issues
Peer reviewed Peer reviewed
Direct linkDirect link
Zwaigenbaum, Lonnie; Thurm, Audrey; Stone, Wendy; Baranek, Grace; Bryson, Susan; Iverson, Jana; Kau, Alice; Klin, Ami; Lord, Cathy; Landa, Rebecca; Rogers, Sally; Sigman, Marian – Journal of Autism and Developmental Disorders, 2007
Detecting early signs of autism is essential for timely diagnosis and initiation of effective interventions. Several research groups have initiated prospective studies of high-risk populations including infant siblings, to systematically collect data on early signs within a longitudinal design. Despite the potential advantages of prospective…
Descriptors: Infants, Siblings, Autism, At Risk Persons
A Prospective Case Series of High-Risk Infants Who Developed Autism
Peer reviewed Peer reviewed
Direct linkDirect link
Bryson, Susan E.; Zwaigenbaum, Lonnie; Brian, Jessica; Roberts, Wendy; Szatmari, Peter; Rombough, Vicki; McDermott, Catherine – Journal of Autism and Developmental Disorders, 2007
The present paper documents the development of autism/autistic spectrum disorder in a consecutive series of nine high-risk infants followed prospectively from 6 months of age. Evidence is provided for two broadly defined subgroups: the first subgroup (n = 6) showed a decrease in IQ between 12 and 24 or 36 months (from average/near average to…
Descriptors: Autism, Infants, Case Studies, At Risk Persons