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Wittke-Thompson, Jacqueline K.; Ambrose, Nicoline; Yairi, Ehud; Roe, Cheryl; Cook, Edwin H.; Ober, Carole; Cox, Nancy J. – Journal of Fluency Disorders, 2007
Genome-wide linkage and association analyses were conducted to identify genetic determinants of stuttering in a founder population in which 48 individuals affected with stuttering are connected in a single 232-person genealogy. A novel approach was devised to account for all necessary relationships to enable multipoint linkage analysis. Regions…
Descriptors: Stuttering, Genetics, Meta Analysis, Religious Cultural Groups
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Ambrose, Nicoline Grinager; Cox, Nancy J.; Yairi, Ehud – Journal of Speech, Language, and Hearing Research, 1997
Immediate and extended families of 66 stuttering children were investigated to determine frequencies of persistent and recovered stuttering. Recovery was far more common among females than males. Recovery or persistence was found to be transmitted, but the two types are not genetically independent, consistent with hypothesis that both forms share…
Descriptors: Children, Etiology, Genetics, Heredity
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Yairi, Ehud; And Others – Journal of Speech and Hearing Research, 1996
This article reviews and critiques the research on possible genetic factors in stuttering. The failure to consider epidemiologic factors is thought to have biased previous research, but recent data provide evidence that spontaneous recovery and chronicity are influenced by genetic factors. Findings support previous conclusions about combined…
Descriptors: Environmental Influences, Epidemiology, Etiology, Genetics
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Subramanian, Anu; Yairi, Ehud – Journal of Communication Disorders, 2006
Stuttering has been considered a heritable disorder since the 1930s. There have been different models of transmission that have been proposed most involving a polygenic component with or without a major locus. In spite of these models, the characteristics being transmitted are not known. This study used two different tasks--a tapping task that is…
Descriptors: Stuttering, Models, Genetics, Experimental Groups
Yairi, Ehud; Ambrose, Nicoline Grinager – PRO-ED, Inc., 2004
This is one of few professional books that addresses the subject of stuttering in young children. This is surprising considering that most cases of stuttering begin in the preschool years and that the prevalence of the disorder in very young children is higher than in any other age group. This excellent and informative text is written for…
Descriptors: Phonology, Stuttering, Parent Participation, Longitudinal Studies