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Wittke-Thompson, Jacqueline K.; Ambrose, Nicoline; Yairi, Ehud; Roe, Cheryl; Cook, Edwin H.; Ober, Carole; Cox, Nancy J. – Journal of Fluency Disorders, 2007
Genome-wide linkage and association analyses were conducted to identify genetic determinants of stuttering in a founder population in which 48 individuals affected with stuttering are connected in a single 232-person genealogy. A novel approach was devised to account for all necessary relationships to enable multipoint linkage analysis. Regions…
Descriptors: Stuttering, Genetics, Meta Analysis, Religious Cultural Groups
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Ambrose, Nicoline Grinager; Cox, Nancy J.; Yairi, Ehud – Journal of Speech, Language, and Hearing Research, 1997
Immediate and extended families of 66 stuttering children were investigated to determine frequencies of persistent and recovered stuttering. Recovery was far more common among females than males. Recovery or persistence was found to be transmitted, but the two types are not genetically independent, consistent with hypothesis that both forms share…
Descriptors: Children, Etiology, Genetics, Heredity