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Since 2006 (last 20 years)3
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Brain Hemisphere Functions3
Conditioning3
Fear3
Role3
Inhibition2
Neurology2
Responses2
Retention (Psychology)2
Animals1
Biochemistry1
Control Groups1
Drug Use1
Learning Processes1
Memory1
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Stimuli1
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Source
Learning & Memory3
Author
Laurent, Vincent3
Westbrook, R. Frederick3
Holtzman-Assif, Orit1
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Journal Articles3
Reports - Research3
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Role of the Basolateral Amygdala in the Reinstatement and Extinction of Fear Responses to a Previously Extinguished Conditioned Stimulus
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Laurent, Vincent; Westbrook, R. Frederick – Learning & Memory, 2010
Four experiments used rats to study the role of the basolateral amygdala (BLA) in the reinstatement and extinction of fear responses (freezing) to a previously extinguished conditioned stimulus (CS). In Experiment 1, BLA inactivation before pairing the extinguished CS with the shock unconditioned stimulus (US) or before US-alone exposure impaired…
Descriptors: Stimuli, Brain Hemisphere Functions, Inhibition, Fear
Blockade of Dopamine Activity in the Nucleus Accumbens Impairs Learning Extinction of Conditioned Fear
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Holtzman-Assif, Orit; Laurent, Vincent; Westbrook, R. Frederick – Learning & Memory, 2010
Three experiments used rats to investigate the role of dopamine activity in learning to inhibit conditioned fear responses (freezing) in extinction. In Experiment 1, rats systemically injected with the D2 dopamine antagonist, haloperidol, froze more across multiple extinction sessions and on a drug-free retention test than control rats. In…
Descriptors: Animals, Fear, Biochemistry, Conditioning
Distinct Contributions of the Basolateral Amygdala and the Medial Prefrontal Cortex to Learning and Relearning Extinction of Context Conditioned Fear
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Laurent, Vincent; Westbrook, R. Frederick – Learning & Memory, 2008
We studied the roles of the basolateral amygdala (BLA) and the medial prefrontal cortex (mPFC) in learning and relearning to inhibit context conditioned fear (freezing) in extinction. In Experiment 1, pre-extinction BLA infusion of the NMDA receptor (NMDAr) antagonist, ifenprodil, impaired the development and retention of inhibition but…
Descriptors: Inhibition, Fear, Conditioning, Brain Hemisphere Functions