Positive behavioral interventions and supports (PBIS) is a widely adopted framework to support the social, emotional, and behavioral growth of all students. This article addresses two key questions related to supporting students with disabilities through PBIS: (a) Why focus on universal classroom PBIS practices?--without support, students with disabilities experience poor outcomes--and (b) How do you implement PBIS in classrooms that support all students?--differentiate and intensify supports.