Despite resistance from faculty, staff, and students, and the sheer magnitude of the effort from a technological and management point of view, some campuses are shifting electronic portfolios away from department-specific initiatives to become institution-wide programs. The move seems to be driven by institutions wanting to focus more deeply and systemically on providing evidence of student mastery of learning outcomes for every area of study, something that all regional higher education accreditation agencies expect a school to do as a part of the accreditation process. However, there are many barriers to overcome before such a practice gets the full participation of faculty, staff, and students. If one is looking to preach the gospel of e-portfolios across the campus and achieve institution-wide adoption, this article presents guidance from those working to make that happen right now at their schools. (Contains 2 online resources.)