Hispanic-Serving Institutions (HSIs) enroll over 60 percent of Latino undergraduates and generally enroll a high enrollment of needy students with relatively limited resources. The federal government has funded the development of HSIs since 1995 to expand and enhance their capacity, quality, and the educational achievement of their Latinos and other low-income students. Is there evidence after 20 years of funding that this purpose is being met? "From Capacity to Success: HSIs, Title V, and Latino Students" examines the impact of 20 years of investment in HSIs and the link of this support on Latino student success. This issue brief provides a snapshot of Latinos in postsecondary education today, as well as a summary of the growth and current profile of HSIs. It also examines linkages between Latino students' educational progress, the institutions where they are concentrated, and the impact of 20 years of federal funding on both student success and the development of HSIs, and offers recommendations for further research to refine the findings from this examination. The research and analysis for this brief were supported by TG. An appendix contains the methodology and limitations of the study.