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Direct linkAddington, Anjene M.; Rapoport, Judith L. – Journal of Child Psychology and Psychiatry, 2012
It was hoped that diagnostic guidelines for, and treatment of, child psychiatric disorders in DSM-5 would be informed by the wealth of clinical genetic research related to neurodevelopmental disorders. In spite of remarkable advances in genetic technology, this has not been the case. Candidate gene, genome-wide association, and rare copy number…
Descriptors: Attention Deficit Hyperactivity Disorder, Schizophrenia, Psychopathology, Neurology
Idol, Jacquelyn R.; Addington, Anjene M.; Long, Robert T.; Rapoport, Judith L.; Green, Eric D. – Journal of Autism and Developmental Disorders, 2008
We characterized a "t"(1;7)(p22;q21) reciprocal translocation in a patient with childhood-onset schizophrenia (COS) and autism using genome mapping and sequencing methods. Based on genomic maps of human chromosome 7 and fluorescence in situ hybridization (FISH) studies, we delimited the region of 7q21 harboring the translocation breakpoint to a…
Descriptors: Schizophrenia, Autism, Children, Genetics
