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Direct linkChenprakhon, Pirom; Panijpan, Bhinyo; Chaiyen, Pimchai – Journal of Chemical Education, 2012
The modulation of ligand p"K"[subscript a] due to its surrounding environment is a crucial feature that controls many biological phenomena. For example, the shift in the p"K"[subscript a] of substrates or catalytic residues at enzyme active sites upon substrate binding often triggers and controls enzymatic reactions. In this work, we developed an…
Descriptors: Biology, Biochemistry, Undergraduate Students, Graduate Students
