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Direct linkBaker, Kathryn D.; McNally, Gavan P.; Richardson, Rick – Learning & Memory, 2012
The NMDA receptor partial agonist d-cycloserine (DCS) enhances the extinction of learned fear in rats and exposure therapy in humans with anxiety disorders. Despite these benefits, little is known about the mechanisms by which DCS promotes the loss of fear. The present study examined whether DCS augments extinction retention (1) through reductions…
Descriptors: Anxiety Disorders, Context Effect, Anxiety, Fear
Chan, Wan Yee Macy; Leung, Hiu T.; Westbrook, R. Frederick; McNally, Gavan P. – Learning & Memory, 2010
In six experiments we studied the effects of a single re-exposure to a conditioned stimulus (CS; "retrieval trial") prior to extinction training (extinction-reconsolidation boundary) on the development of and recovery from fear extinction. A single retrieval trial prior to extinction training significantly augmented the renewal and reinstatement…
Descriptors: Stimuli, Learning Processes, Context Effect, Classical Conditioning
