Extending an earlier study that found high self-esteem to modify the impact of otherwise maladaptive perfectionism on depression, the current study used adult attachment theory to explore the link between perfectionism, self-esteem, and depression in college students. Results indicated that self-esteem buffered the effects of maladaptive perfectionism on depression and that adult attachment security moderated the association between perfectionistic self-doubt and self-esteem. Counseling implications of these findings are discussed.