This report profiles participant outcomes of the classic Upward Bound (UB) and Upward Bound Math-Science (UBMS) programs. The UB and UBMS programs provide academic and other support services for high school participants preparing to enter college. Upward Bound's goal is to increase the rate at which program participants complete high school and enroll in and complete programs of postsecondary education. UBMS has an additional goal, to help students recognize and develop their potential to excel in the fields of math and science and pursue postsecondary degrees in these fields. The UB and UBMS programs serve high school students from low-income families and from families in which neither parent holds a bachelor's degree--that is, potentially first-generation college students. Annually, UB projects each serve between 50 and 150 participants; UBMS projects each serve between 50 and 75 participants. This report brings together demographic data and information on program outcomes for the UB and UBMS programs and for the first time presents data on postsecondary enrollment rates for UB and UBMS participants who were expected to graduate high school during the 2004-05 academic year. Moreover, with data now available for the 2000-01, 2001-02, 2002-03, 2003-04, 2004-05, and 2005-06 project years, this report includes information on the academic progress of a complete cohort--one that includes a full range of participants, from those who entered the program as ninth-graders or rising ninth-graders to those who joined UB or UBMS later in high school. [This report was prepared for Federal TRIO Programs, Office of Postsecondary Education.]